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PNC-27

£146.99£153.79

Buy PNC-27 Peptide Vial

PNC-27 is a peptide designed to treat cancer by targeting and destroying the cell membranes of cancer cells while leaving healthy cells unharmed. It works by binding to the HDM-2 protein found in cancer cells, which leads to the formation of membrane pores that cause cell death.

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547 in stock

Description

PNC-27 Peptide Vial 5mg  United Kingdom

This product is intended for research purposes only. To be used by trained professionals only.

PNC-27 is a synthetic peptide that research suggests triggers necrosis in cancerous cells, resulting in cell death. In addition, an HDM-2 binding domain in the peptide allows it to membranolyze cancer cells and kill them [1].

United Kingdom Scientific studies suggest PNC-27 peptide appears to be highly effective in treating a variety of cancers, including breast cancer, melanoma, pancreatic cancer, and leukaemia, according to experiments on animal subjects [2].

Some United Kingdom studies have suggested in contrast to chemotherapy, which targets healthy cells, the PNC-27 peptide targets cancer cells. When it attaches to cancer cells, it makes holes in their membranes, causing them to die quickly.

Scientists had intended to use PNC-27 peptide to fight HIV until it was discovered that it could also be used to destroy cancer cells while not harming healthy ones. Few clinical trials using PNC-27 since then have shown that it is effective in combating cancer [3].

PNC 27’s mechanism of action, according to the studies, is caused by the formation of oligomeric pores in cancer cells’ plasma membranes. Researchers, therefore, concluded that these findings confirm cancer cells’ unique localization of MDM2 variants. Consequently, it was also stated that the future anticancer treatment using the PNC-27 peptide shows excellent promise.


References:

[1] http://www.annclinlabsci.org/ content/44/3/241.full

[2] https://touroscholar.touro.edu/ sjlcas/vol13/iss2/7/

[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5359827/


Molecular Formula: C188H293N53O44S

Molecular Weight: 4031.7

Storage: Lyophilized peptides stored below -18°C.

Research use only. Not for human or animal consumption!

PNC-27 HPLC 2023 Certificates_DIRECT PEPTIDES

 

 

 

 

 

 

 

 


DISCLAIMER: We do not supply peptides to any individual under the age of 21. You must be a licensed and qualified healthcare practitioner. Our team of dedicated professionals are committed to providing an extensive range of products used ONLY in the process of laboratory research by responsible trained and professional individuals. All products listed on this website (https://united-kingdom.direct-peptides.com) and provided through Direct Peptides are intended for laboratory research purposes only. The products listed on this website are NOT for human or animal consumption or ingestion of any kind.


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