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PNC-27 5mg Pre Mixed


Nontoxic protein that can selectively bind to receptors present in cancer cells to cause cell death.

Pre Mixed Cartridge and Kit:
1 x Cartridge (The cartridge is premixed with the peptide vial of your choice and Bacteriostatic Water)
* 1 x Peptide Cartridge Pen
* 1 x Pen Carry Case
* 3 x Pen Needle Tips

Single Mixed Cartridges (1,2 & 3) Come with:

* 1,2 or 3 x Cartridge (The cartridge is premixed with the peptide vial of your choice and Bacteriostatic Water)
* 3 x Pen Needle Tips
The single 1,2 & 3 cartridges do not come with a kit.

Buy 10 and get 10% Discount

663 in stock


PNC-27 Pre Mixed Peptide Pen 5mg  United Kingdom

This product is intended for research purposes only. To be used by trained professionals only.

PNC-27 is a peptide that has sparked interest in the scientific community due to its anti-cancer capabilities. This membrane-active peptide contains an HDM-2-binding domain that correlates to p53 residues, a protein known for its function in cancer prevention, as well as a transmembrane-penetrating sequence [1].

As an intact peptide, PNC-27 pre mixed peptide has been shown in studies to promote cancer cell necrosis. PNC-27 has been shown in United Kingdom studies to produce these effects in a number of breast cancer cells, including MCF-7, MDA-MB-468, and MDA-MB-157 [1]. PNC-27 interacts to HDM-2 in cancer cells when treated with this peptide, according to additional research. One study, for example, incubated double-fluorophore-labelled PNC-27 (50 g/ml) with 1106 MIA-PaCa-2 cells for 4 hours, indicating substantial interactions [2].

PNC-27 pre mixed peptide has also being investigated as a potential technique for early cancer detection. One study looked examined PNC-27 peptide attached PEI-superparamagnetic iron oxide nanoparticles (SPIONs) as a dual targeting agent for cancer detection in the early stages [3].

PNC-27’s efficacy against colon adenocarcinoma and ovarian cancer has also been studied in vitro and in vivo. various trials have yielded promising results, indicating that PNC-27 peptide has the potential to be an effective alternative treatment for various types of malignancies [4].

However, despite its promise, further research is required to properly understand the potential advantages and hazards of PNC-27 pre mixed peptide.


[1] https://link.springer.com/article/ 10.1007/s00280-009-1166-7

[2] https://www.pnas.org/doi/abs/ 10.1073/pnas.0909364107

[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC9588323/

[4] https://www.sciencedirect.com/ science/article/abs/pii/S17732247 22000892

Molecular Formula: C188H293N53O44S

Molecular Weight: 4031.7

Storage: Lyophilized peptides stored below -18°C.

Research use only. Not for human or animal consumption!

PNC-27 HPLC 2023 Certificates_DIRECT PEPTIDES









DISCLAIMER: We do not supply peptides to any individual under the age of 21. You must be a licensed and qualified healthcare practitioner. Our team of dedicated professionals are committed to providing an extensive range of products used ONLY in the process of laboratory research by responsible trained and professional individuals. All products listed on this website (https://united-kingdom.direct-peptides.com) and provided through Direct Peptides are intended for laboratory research purposes only. The products listed on this website are NOT for human or animal consumption or ingestion of any kind.

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