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B7-33 Nasal Spray


Buy B7-33 Nasal Spray

B7-33 possesses potent anti-fibrotic effects. Reduced fibrosis can help with both chronic and acute conditions such as heart failure, lung inflammation, and kidney inflammation. B7-33 has been proven in animal experiments to reduce fibrosis, resulting in longer survival after injury and treatment for heart failure.

B7-33 15ml – Contains: 4mg

B7-33 30ml – Contains: 8mg

Buy 10 and get 10% Discount

481 in stock


B7-33 Peptide Nasal Spray United Kingdom

This product is intended for research purposes only. To be used by trained professionals only.

H2-relaxin, a more significant naturally occurring protein, is the source of B7-33, a soluble single-chain peptide. B7-33 nasal spray keeps relaxin’s anti-fibrotic properties due to it not increasing cAMP.

B7-33 has powerful anti-fibrotic properties [1]. Chronic and acute diseases like heart failure, inflammation of the lungs or the kidneys can all be helped by reducing fibrosis. B7-33 nasal spray has been shown in animal studies to minimise fibrosis resulting in prolonged survival following injury and providing the treatment for heart failure.

In addition, this peptide stimulates ERK1/2 phosphorylation, which promotes MMP2 expression and collagen degradation.

In the event of a cardiac injury, it appears to lessen the amount of scar tissue that forms [2]. Furthermore, the treatment of vascular disorders and preeclampsia of pregnancy have also shown promising results.

Peptides like B7-33 are synthesised from the human H2-relaxin protein.

In addition, relaxin, insulin-like peptide 3, and insulin-like peptide 5 — are all derivatives of the human H2-relaxin protein. Insulin-like peptides, such as these, have affected the cardiovascular, musculoskeletal, and reproductive systems and others.

Four endogenous receptors (RXFP1/2 and RXFP3/4) exist for the relaxin family peptides. However, relaxin proteins are not the only ones that can bind to the receptors of the relaxin system. Several insulin-like peptides, as well as cAMP and orexin, can all stimulate these receptors.

Anti-inflammatory, antioxidant, and wound healing properties have all been demonstrated for agonists. Relaxin was found to be the primary ligand for these receptors after these findings.

United Kingdom Researchers have discovered that relaxin dilates blood vessels, stimulates blood vessel growth, and acts as antihypertrophic. Because of its anti-fibrotic properties, relaxin and its derivatives have been the subject of extensive research to treat acute heart failure and other fibrotic diseases.


[1] https://pubs.acs.org/doi/abs/ 10.1021/acsami.9b17859

[2] https://pubmed.ncbi.nlm.nih.gov/ 32295457/


B7-33 HPLC 2023 Certificates_DIRECT PEPTIDES









DISCLAIMER: We do not supply peptides to any individual under the age of 21. You must be a licensed and qualified healthcare practitioner. Our team of dedicated professionals are committed to providing an extensive range of products used ONLY in the process of laboratory research by responsible trained and professional individuals. All products listed on this website (https://united-kingdom.direct-peptides.com) and provided through Direct Peptides are intended for laboratory research purposes only. The products listed on this website are NOT for human or animal consumption or ingestion of any kind.

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