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Mots-c 10mg Pre Mixed

£36.40£104.21

MOTS-c is a 16-amino acid mitochondrial-encoded peptide that is encoded from the mitochondrial genome’s 12S rRNA region. This peptide is important in establishing metabolic homeostasis, primarily via activating AMPK and directly controlling metabolic activities throughout the body.

Pre Mixed Cartridge and Kit:

  • 
1 x Cartridge (The cartridge is premixed with the peptide vial of your choice and Bacteriostatic Water)
  • 1 x Peptide Cartridge Pen
  • 1 x Pen Carry Case
  • 3 x Pen Needle Tips

Single Mixed Cartridges (1,2 & 3) Come with:

  • 1,2 or 3 x Cartridge (The cartridge is premixed with the peptide vial of your choice and Bacteriostatic Water)
  • 3 x Pen Needle Tips

The single 1,2 & 3 cartridges do not come with a kit.

Buy 10 and get 10% Discount

867 in stock

Description

Mots-c Pre Mixed Pen 10mg United Kingdom

This product is intended for research purposes only. To be used by trained professionals only.

MOTS-c pre mixed peptide is a new mitochondrial-derived peptide that has emerged as a key regulator of metabolic homeostasis, especially in muscle and fat metabolism. MOTS-c, which consists of 16 amino acids, targets skeletal muscle and improves glucose metabolism, making it an important factor in metabolic regulation [1].

MOTS-c has also been linked to longevity, with particular polymorphisms in the MOTS-c encoding area perhaps leading to long life [2]. The United Kingdom scientific community is becoming increasingly interested in this peptide’s potential function in ageing and age-related illnesses [3]. Furthermore, new study has revealed the therapeutic potential of MOTS-c pre mixed peptide. It has been found to increase survival and decrease bacterial load in MRSA-infected mice, boosting macrophage bactericidal activity [4]. This could imply that MOTS-c has a greater involvement in immune function and infection control.

MOTS-c translation occurs primarily in the cytoplasm and its sequence, particularly the first 11 residues, is highly conserved in terms of therapeutic exploitation. This could affect drug development and disease treatment tactics. MOTS-c has also been demonstrated to modulate adipose homeostasis, reducing metabolic dysfunction caused by ovariectomy [5]. The action of this peptide on the insulin signalling system may make it an appealing target for metabolic disorders therapies.

In United Kingdom clinical studies, the administration of MOTS-c pre mixed peptide has been shown to protect against unfavourable cardiac remodelling and dysfunction under pressure overload conditions, implying a potential involvement in cardiovascular health. In response to metabolic stress, MOTS-c can translocate to the nucleus and control nuclear gene expression [6]. This characteristic emphasises the peptide’s ability to regulate cellular activities other than metabolism.


References:

[1] https://www.sciencedirect.com/ science/article/abs/pii/S08915849 16302507

[2] https://onlinelibrary.wiley.com/ doi/full/10.1111/acel.12389

[3] https://www.mdpi.com/1422-0067/23/19/11991

[4] https://www.sciencedirect.com/ science/article/abs/pii/S0161589 017305461

[5] https://link.springer.com/article/ 10.1007/s00109-018-01738-w

[6] https://www.cell.com/cell-metabolism/ pdf/S1550-4131(18)30390-5.pdf


Sequence:Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

Molecular Formula: C101H152N28O22S2

Molecular Weight: 2174.64 f/mol

Storage: Lyophilized peptides to be stored below -18°C

Research use only. Not for human or animal consumption!

MOTS-C HPLC 2023 Certificates_DIRECT PEPTIDES

 

 

 

 

 

 

 

 


DISCLAIMER: We do not supply peptides to any individual under the age of 21. You must be a licensed and qualified healthcare practitioner. Our team of dedicated professionals are committed to providing an extensive range of products used ONLY in the process of laboratory research by responsible trained and professional individuals. All products listed on this website (https://united-kingdom.direct-peptides.com) and provided through Direct Peptides are intended for laboratory research purposes only. The products listed on this website are NOT for human or animal consumption or ingestion of any kind.


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