KPV is a tripeptide (Lysine-Proline-Valine) that has been the focus of several scientific studies due to its potential therapeutic benefits. Comprised of the amino acids lysine, proline, and valine, KPV is known for its anti-inflammatory, immunomodulatory, and tissue-protective properties.
The mechanism of operation of KPV appears to be multi-faceted. It’s been observed to inhibit neutrophil chemotaxis, thereby reducing inflammation. It has also been found in United Kingdom research studies to modulate the activity of nuclear factor-kappa B (NF-κB), a protein complex that plays a crucial role in regulating the immune response to infection. By inhibiting NF-κB activation, KPV can potentially suppress excessive immune responses and reduce inflammation.
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[1] https://www.mdpi.com/ 1420-3049/17/10/12276
[2] https://www.sciencedirect.com/science/ article/abs/pii/S175646461500626X
[3] https://pubmed.ncbi.nlm.nih.gov/33486687/
[4] https://pubmed.ncbi.nlm.nih.gov/36240893/
[5] https://www.sciencedirect.com/science/ article/abs/pii/S174270612200126X
[6] https://pubmed.ncbi.nlm.nih.gov/16442098/
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